Prostate Diagnostics: PSA Density & Volume
Prostate volume is a key metric in urological diagnostics. It helps doctors interpret PSA levels, diagnose Benign Prostatic Hyperplasia (BPH), and assess cancer risk.
What is PSA Density?
PSA Density = Total PSA (ng/mL) / Prostate Volume (cc)
PSA (Prostate-Specific Antigen) is a protein produced by the prostate. Larger prostates naturally produce more PSA. PSA Density helps distinguish between BPH (benign enlargement) and prostate cancer.
- Low Density (<0.15): Often suggests BPH, especially if the prostate is large.
- High Density (>0.15): May indicate a higher suspicion of prostate cancer, as cancer cells produce more PSA per unit of volume than benign tissue.
Normal Prostate Size by Age
The prostate gland grows naturally with age. What is considered "normal" changes as men get older.
Source: Berry, S. J., et al. (1984). The development of human benign prostatic hyperplasia with age. Journal of Urology.
| Age Group | Average Volume (cc) | Status |
|---|---|---|
| 20 - 30 years | 20 - 25 cc | Normal |
| 31 - 50 years | 25 - 30 cc | Normal |
| 51 - 70 years | 30 - 40 cc | Mild Enlargement |
| > 70 years | 40+ cc | Common BPH |
How is Volume Measured?
Measurements are typically taken via:
- TRUS (Transrectal Ultrasound): The most common method.
- MRI (Magnetic Resonance Imaging): Provides highly detailed images and is increasingly used for precise volume estimation before biopsy.
Calculate Your PSA Density
Have your measurements ready? Use our calculator to compute prostate volume and PSA density instantly.